Flounder health status in the Seine Bay. A multibiomarker study.
Identifieur interne : 003327 ( Main/Exploration ); précédent : 003326; suivant : 003328Flounder health status in the Seine Bay. A multibiomarker study.
Auteurs : C. Minier [France] ; F. Levy ; D. Rabel ; G. Bocquené ; D. Godefroy ; T. Burgeot ; F. LeboulengerSource :
- Marine environmental research [ 0141-1136 ]
English descriptors
- KwdEn :
- MESH :
- chemical , metabolism : Acetylcholinesterase, Cytochrome P-450 CYP1A1.
- drug effects : Sex Differentiation.
- physiology : Flounder.
- chemical , toxicity : Water Pollutants, Chemical.
- Animals, Biomarkers, Drug Resistance, Female, Health Status, Male.
Abstract
The Seine Bay is used as a pilot area to assess the usefulness of monitoring programmes using a suite of biological measurements. These biomarkers included ethoxyresorfin-O-deethylase (EROD) and acetylcholinesterase (AChE) activities, multixenobiotic resistance (MXR) protein expression level assessment and gonad histopathology. Samples of European flounder collected in three sites close to the Seine Estuary in late September 1998 showed that 8% of the males were intersex, i.e. had gonads with both male and female tissues. Another 10% of individuals, identified as male by morphological observation during sampling, showed only female tissues on histological sections. These dramatic changes were associated with different patterns of EROD activity, MXR expression or AChE activity inhibition that might reflect shorter time effects of xenobiotics and constitute a starting point to integrate biological responses for the assessment of the health status of flounder in the Seine Bay.
PubMed: 11460721
Affiliations:
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Levy</name></author><author><name sortKey="Rabel, D" sort="Rabel, D" uniqKey="Rabel D" first="D" last="Rabel">D. Rabel</name></author><author><name sortKey="Bocquene, G" sort="Bocquene, G" uniqKey="Bocquene G" first="G" last="Bocquené">G. Bocquené</name></author><author><name sortKey="Godefroy, D" sort="Godefroy, D" uniqKey="Godefroy D" first="D" last="Godefroy">D. Godefroy</name></author><author><name sortKey="Burgeot, T" sort="Burgeot, T" uniqKey="Burgeot T" first="T" last="Burgeot">T. Burgeot</name></author><author><name sortKey="Leboulenger, F" sort="Leboulenger, F" uniqKey="Leboulenger F" first="F" last="Leboulenger">F. Leboulenger</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="????"><PubDate><MedlineDate>2000 Jul-Dec</MedlineDate></PubDate></date><idno type="RBID">pubmed:11460721</idno><idno type="pmid">11460721</idno><idno type="wicri:Area/PubMed/Corpus">000401</idno><idno type="wicri:Area/PubMed/Curation">000401</idno><idno type="wicri:Area/PubMed/Checkpoint">000401</idno><idno type="wicri:Area/Ncbi/Merge">000035</idno><idno type="wicri:Area/Ncbi/Curation">000035</idno><idno type="wicri:Area/Ncbi/Checkpoint">000035</idno><idno type="wicri:doubleKey">0141-1136::Minier C:flounder:health:status</idno><idno type="wicri:Area/Main/Merge">003414</idno><idno type="wicri:Area/Main/Curation">003327</idno><idno type="wicri:Area/Main/Exploration">003327</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Flounder health status in the Seine Bay. A multibiomarker study.</title><author><name sortKey="Minier, C" sort="Minier, C" uniqKey="Minier C" first="C" last="Minier">C. Minier</name><affiliation wicri:level="3"><nlm:affiliation>Laboratory of Ecotoxicology, University of Le Havre, 2BP540, 25 rue Philippe Lebon, F-76058 Le Havre, France. minier@univ-lehavre.fr</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Laboratory of Ecotoxicology, University of Le Havre, 2BP540, 25 rue Philippe Lebon, F-76058 Le Havre</wicri:regionArea><placeName><region type="region" nuts="2">Région Normandie</region><region type="old region" nuts="2">Haute-Normandie</region><settlement type="city">Le Havre</settlement></placeName></affiliation></author><author><name sortKey="Levy, F" sort="Levy, F" uniqKey="Levy F" first="F" last="Levy">F. Levy</name></author><author><name sortKey="Rabel, D" sort="Rabel, D" uniqKey="Rabel D" first="D" last="Rabel">D. Rabel</name></author><author><name sortKey="Bocquene, G" sort="Bocquene, G" uniqKey="Bocquene G" first="G" last="Bocquené">G. Bocquené</name></author><author><name sortKey="Godefroy, D" sort="Godefroy, D" uniqKey="Godefroy D" first="D" last="Godefroy">D. Godefroy</name></author><author><name sortKey="Burgeot, T" sort="Burgeot, T" uniqKey="Burgeot T" first="T" last="Burgeot">T. Burgeot</name></author><author><name sortKey="Leboulenger, F" sort="Leboulenger, F" uniqKey="Leboulenger F" first="F" last="Leboulenger">F. Leboulenger</name></author></analytic><series><title level="j">Marine environmental research</title><idno type="ISSN">0141-1136</idno></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acetylcholinesterase (metabolism)</term><term>Animals</term><term>Biomarkers</term><term>Cytochrome P-450 CYP1A1 (metabolism)</term><term>Drug Resistance</term><term>Female</term><term>Flounder (physiology)</term><term>Health Status</term><term>Male</term><term>Sex Differentiation (drug effects)</term><term>Water Pollutants, Chemical (toxicity)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Acetylcholinesterase</term><term>Cytochrome P-450 CYP1A1</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Sex Differentiation</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Flounder</term></keywords><keywords scheme="MESH" type="chemical" qualifier="toxicity" xml:lang="en"><term>Water Pollutants, Chemical</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Biomarkers</term><term>Drug Resistance</term><term>Female</term><term>Health Status</term><term>Male</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The Seine Bay is used as a pilot area to assess the usefulness of monitoring programmes using a suite of biological measurements. These biomarkers included ethoxyresorfin-O-deethylase (EROD) and acetylcholinesterase (AChE) activities, multixenobiotic resistance (MXR) protein expression level assessment and gonad histopathology. Samples of European flounder collected in three sites close to the Seine Estuary in late September 1998 showed that 8% of the males were intersex, i.e. had gonads with both male and female tissues. Another 10% of individuals, identified as male by morphological observation during sampling, showed only female tissues on histological sections. These dramatic changes were associated with different patterns of EROD activity, MXR expression or AChE activity inhibition that might reflect shorter time effects of xenobiotics and constitute a starting point to integrate biological responses for the assessment of the health status of flounder in the Seine Bay.</div></front></TEI><affiliations><list><country><li>France</li></country><region><li>Haute-Normandie</li><li>Région Normandie</li></region><settlement><li>Le Havre</li></settlement></list><tree><noCountry><name sortKey="Bocquene, G" sort="Bocquene, G" uniqKey="Bocquene G" first="G" last="Bocquené">G. Bocquené</name><name sortKey="Burgeot, T" sort="Burgeot, T" uniqKey="Burgeot T" first="T" last="Burgeot">T. Burgeot</name><name sortKey="Godefroy, D" sort="Godefroy, D" uniqKey="Godefroy D" first="D" last="Godefroy">D. Godefroy</name><name sortKey="Leboulenger, F" sort="Leboulenger, F" uniqKey="Leboulenger F" first="F" last="Leboulenger">F. Leboulenger</name><name sortKey="Levy, F" sort="Levy, F" uniqKey="Levy F" first="F" last="Levy">F. Levy</name><name sortKey="Rabel, D" sort="Rabel, D" uniqKey="Rabel D" first="D" last="Rabel">D. Rabel</name></noCountry><country name="France"><region name="Région Normandie"><name sortKey="Minier, C" sort="Minier, C" uniqKey="Minier C" first="C" last="Minier">C. Minier</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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